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Fundamental role for HIF-1α in constitutive expression of human β defensin-1
Antimicrobial peptides are secreted by the intestinal epithelium to defend from microbial threats. The role of human β defensin-1 (hBD-1) is notable because its gene (beta-defensin 1 (DEFB1)) is constitutively expressed and its antimicrobial activity is potentiated in the low-oxygen environment that...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740147/ https://ncbi.nlm.nih.gov/pubmed/23462909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.6 |
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