Aggregation Modulators Interfere with Membrane Interactions of β(2)-Microglobulin Fibrils

Amyloid fibril accumulation is a pathological hallmark of several devastating disorders, including Alzheimer’s disease, prion diseases, type II diabetes, and others. Although the molecular factors responsible for amyloid pathologies have not been deciphered, interactions of misfolded proteins with c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sheynis, Tania, Friediger, Anat, Xue, Wei-Feng, Hellewell, Andrew L., Tipping, Kevin W., Hewitt, Eric W., Radford, Sheena E., Jelinek, Raz
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2013
Schlagworte:
Proteins and Nucleic Acids
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736666/
https://ncbi.nlm.nih.gov/pubmed/23931322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.06.015
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