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Glimpses of the molecular mechanisms of β(2)-microglobulin fibril formation in vitro: Aggregation on a complex energy landscape
β(2)-microglobulin (β(2)m) is a 99-residue protein that aggregates to form amyloid fibrils in dialysis-related amyloidosis. The protein provides a powerful model for exploration of the structural molecular mechanisms of fibril formation from a full-length protein in vitro. Fibrils have been assemble...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier Science B.V
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734061/ https://ncbi.nlm.nih.gov/pubmed/19433089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.05.005 |
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