Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication

BRAF mutation in colorectal cancer is associated with microsatellite instability (MSI) through its relationship with high-level CpG island methylator phenotype (CIMP) and MLH1 promoter methylation. MSI and BRAF mutation analyses are routinely used for familial cancer risk assessment. To clarify clin...

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Bibliografske podrobnosti
Main Authors: Lochhead, Paul, Kuchiba, Aya, Imamura, Yu, Liao, Xiaoyun, Yamauchi, Mai, Nishihara, Reiko, Qian, Zhi Rong, Morikawa, Teppei, Shen, Jeanne, Meyerhardt, Jeffrey A., Fuchs, Charles S., Ogino, Shuji
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Brief Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735463/
https://ncbi.nlm.nih.gov/pubmed/23878352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt173
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