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Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication
BRAF mutation in colorectal cancer is associated with microsatellite instability (MSI) through its relationship with high-level CpG island methylator phenotype (CIMP) and MLH1 promoter methylation. MSI and BRAF mutation analyses are routinely used for familial cancer risk assessment. To clarify clin...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735463/ https://ncbi.nlm.nih.gov/pubmed/23878352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt173 |
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