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Specific Mutations in KRAS Codons 12 and 13, and Patient Prognosis in 1075 BRAF-wild-type Colorectal Cancers

PURPOSE: To assess prognostic roles of various KRAS oncogene mutations in colorectal cancer, BRAF mutation status must be controlled for because BRAF mutation is associated with poor prognosis, and almost all BRAF mutants are present among KRAS-wild-type tumors. Taking into account experimental data...

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Detalhes bibliográficos
Main Authors: Imamura, Yu, Morikawa, Teppei, Liao, Xiaoyun, Lochhead, Paul, Kuchiba, Aya, Yamauchi, Mai, Qian, Zhi Rong, Nishihara, Reiko, Meyerhardt, Jeffrey A., Haigis, Kevin M., Fuchs, Charles S., Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624899/
https://ncbi.nlm.nih.gov/pubmed/22753589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3210
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