Specific Mutations in KRAS Codons 12 and 13, and Patient Prognosis in 1075 BRAF-wild-type Colorectal Cancers

PURPOSE: To assess prognostic roles of various KRAS oncogene mutations in colorectal cancer, BRAF mutation status must be controlled for because BRAF mutation is associated with poor prognosis, and almost all BRAF mutants are present among KRAS-wild-type tumors. Taking into account experimental data...

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Huvudupphovsmän: Imamura, Yu, Morikawa, Teppei, Liao, Xiaoyun, Lochhead, Paul, Kuchiba, Aya, Yamauchi, Mai, Qian, Zhi Rong, Nishihara, Reiko, Meyerhardt, Jeffrey A., Haigis, Kevin M., Fuchs, Charles S., Ogino, Shuji
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624899/
https://ncbi.nlm.nih.gov/pubmed/22753589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3210
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