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MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of ΔNP63α and promotes mesenchymal-to-epithelial transition

During reproductive life, the mammary epithelium undergoes consecutive cycles of proliferation, differentiation and apoptosis. Doing so relies on the retained proliferative capacity, prolonged lifespan and developmental potency of mammary stem cells (MaSCs). ΔNp63α, the predominant TP63 isoform in m...

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書誌詳細
主要な著者: DeCastro, A J, Dunphy, K A, Hutchinson, J, Balboni, A L, Cherukuri, P, Jerry, D J, DiRenzo, J
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734833/
https://ncbi.nlm.nih.gov/pubmed/23449450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.37
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