MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of ΔNP63α and promotes mesenchymal-to-epithelial transition

During reproductive life, the mammary epithelium undergoes consecutive cycles of proliferation, differentiation and apoptosis. Doing so relies on the retained proliferative capacity, prolonged lifespan and developmental potency of mammary stem cells (MaSCs). ΔNp63α, the predominant TP63 isoform in m...

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Autors principals: DeCastro, A J, Dunphy, K A, Hutchinson, J, Balboni, A L, Cherukuri, P, Jerry, D J, DiRenzo, J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734833/
https://ncbi.nlm.nih.gov/pubmed/23449450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.37
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