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ΔNp63α promotes cellular quiescence via induction and activation of Notch3

Genetic analysis of TP63 indicates that ΔNp63 isoforms are required for preservation of self-renewing capacity in the stem cell compartments of diverse epithelial structures; however, the underlying cellular and molecular mechanisms remain incompletely defined. Cellular quiescence is a common featur...

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Detalhes bibliográficos
Principais autores: Kent, Sierra, Hutchinson, Justine, Balboni, Amanda, DeCastro, Andrew, Cherukuri, Pratima, DiRenzo, James
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218621/
https://ncbi.nlm.nih.gov/pubmed/21912215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.18.17300
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