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Evaluation of N-Phenyl Homopiperazine Analogs as Potential Dopamine D(3) Receptor Selective Ligands

A series of N-(2-methoxyphenyl)homopiperazine analogs was prepared and their affinities for dopamine D(2), D(3), and D(4) receptors were measured using competitive radioligand binding assays. Several ligands exhibited high binding affinity and selectivity for the D(3) dopamine receptor compared to t...

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Bibliografiske detaljer
Main Authors: Li, Aixiao, Mishra, Yogesh, Malik, Maninder, Wang, Qi, Li, Shihong, Taylor, Michelle, Reichert, David E., Luedtke, Robert R., Mach, Robert H.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733449/
https://ncbi.nlm.nih.gov/pubmed/23618707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.03.074
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