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Evaluation of N-Phenyl Homopiperazine Analogs as Potential Dopamine D(3) Receptor Selective Ligands

A series of N-(2-methoxyphenyl)homopiperazine analogs was prepared and their affinities for dopamine D(2), D(3), and D(4) receptors were measured using competitive radioligand binding assays. Several ligands exhibited high binding affinity and selectivity for the D(3) dopamine receptor compared to t...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Li, Aixiao, Mishra, Yogesh, Malik, Maninder, Wang, Qi, Li, Shihong, Taylor, Michelle, Reichert, David E., Luedtke, Robert R., Mach, Robert H.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733449/
https://ncbi.nlm.nih.gov/pubmed/23618707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.03.074
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