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Synthesis and in vitro pharmacological evaluation of indolyl carboxylic amide analogues as D(3) dopamine receptor selective ligands()
A series of substituted 1H-indolyl carboxylic acid amides that contain a N-(2-methoxyphenyl)piperazine or N-(2-fluoroethoxy)piperazine group were synthesized and their affinities for human dopamine D(2), D(3), and D(4) receptors were determined. Two of these compounds, 14a and 14b, displayed high bi...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804115/ https://ncbi.nlm.nih.gov/pubmed/24156012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3MD00098B |
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