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Synthesis and in vitro pharmacological evaluation of indolyl carboxylic amide analogues as D(3) dopamine receptor selective ligands()

A series of substituted 1H-indolyl carboxylic acid amides that contain a N-(2-methoxyphenyl)piperazine or N-(2-fluoroethoxy)piperazine group were synthesized and their affinities for human dopamine D(2), D(3), and D(4) receptors were determined. Two of these compounds, 14a and 14b, displayed high bi...

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Autors principals: Tu, Zhude, Li, Shihong, Li, Aixiao, Taylor, Michelle, Ho, David, Malik, Maninder, Luedtke, Robert R., Mach, Robert H.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804115/
https://ncbi.nlm.nih.gov/pubmed/24156012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3MD00098B
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