A carregar...
Synthesis and Structure-Activity Relationship Studies of Conformationally Flexible Tetrahydroisoquinolinyl Triazole Carboxamide and Triazole Substituted Benzamide Analogues as σ(2) Receptor Ligands
Two novel classes of compounds targeting the sigma-2 (σ(2)) receptor were synthesized, and their bioactivities to binding σ(1) and σ(2) receptors were measured. Four novel triazole carboxamide analogues, 24d, 24e, 24f, and 39c, demonstrated high affinity and selectivity for the σ(2) receptor. These...
Na minha lista:
| Publicado no: | J Med Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6818095/ https://ncbi.nlm.nih.gov/pubmed/24821398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5001453 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|