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Radiosynthesis and biological evaluation of a promising σ(2)-receptor ligand radiolabeled with fluorine-18 or iodine-125 as a PET/SPECT probe for imaging breast cancer
Sigma-2 receptors represent an endogenous marker for proliferation in solid tumors. The high affinity, high selectivity σ(2) receptor ligand N-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-2-(2-fluoroethoxy)-5-iodo-3-methoxybenzamide (3) was separately radiolabeled with F-18 and I-125. Th...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937058/ https://ncbi.nlm.nih.gov/pubmed/20594864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2010.06.004 |
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