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Automated radiosynthesis of [(11)C]morphine for clinical investigation
To meet a multiple-dose clinical evaluation of the P-gp modulation of [(11)C]morphine delivery into the human brain, radiosynthesis of [(11)C]morphine was accomplished on an automated system by N-methylation of normorphine with [(11)C]CH(3)I. A methodology employing optimized solid-phase extraction...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026438/ https://ncbi.nlm.nih.gov/pubmed/21112214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2010.11.003 |
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