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Functional assays to define agonists and antagonists of the sigma-2 receptor
The sigma-2 receptor has been identified as a biomarker in proliferating tumors. Up to date there is no well-established functional assay for defining sigma-2 agonists and antagonists. Many sigma-2 ligands with diverse structures have been shown to induce cell death in a variety of cancer cells by t...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3923374/ https://ncbi.nlm.nih.gov/pubmed/24333652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2013.12.008 |
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