More active human L1 retrotransposons produce longer insertions

The vast majority of L1 insertions are 5′ truncated and thus inactive. Yet, the mechanism of 5′ truncation is unknown. To examine whether the frequency of L1 retrotransposition is directly correlated with the length of genomic L1 insertions, we used a cell culture assay to measure retrotransposition...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Farley, Alexander H., Luning Prak, Eline T., Kazazian, Haig H.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 2004
Assuntos:	Articles
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373329/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh202
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