More active human L1 retrotransposons produce longer insertions

The vast majority of L1 insertions are 5′ truncated and thus inactive. Yet, the mechanism of 5′ truncation is unknown. To examine whether the frequency of L1 retrotransposition is directly correlated with the length of genomic L1 insertions, we used a cell culture assay to measure retrotransposition...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Farley, Alexander H., Luning Prak, Eline T., Kazazian, Haig H.
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2004
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373329/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh202
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