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Twin Priming: A Proposed Mechanism for the Creation of Inversions in L1 Retrotransposition

L1 retrotransposons are pervasive in the human genome. Approximately 25% of recent L1 insertions in the genome are inverted and truncated at the 5′ end of the element, but the mechanism of L1 inversion has been a complete mystery. We analyzed recent L1 inversions from the genomic database and discov...

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Detalhes bibliográficos
Main Authors: Ostertag, Eric M., Kazazian, Haig H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC311219/
https://ncbi.nlm.nih.gov/pubmed/11731496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.205701
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