Human L1 Retrotransposition: cis Preference versus trans Complementation
Long interspersed nuclear elements (LINEs or L1s) comprise approximately 17% of human DNA; however, only about 60 of the ∼400,000 L1s are mobile. Using a retrotransposition assay in cultured human cells, we demonstrate that L1-encoded proteins predominantly mobilize the RNA that encodes them. At muc...
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| Опубликовано в:: | Mol Cell Biol |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158327/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.4.1429-1439.2001 |
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