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More active human L1 retrotransposons produce longer insertions

The vast majority of L1 insertions are 5′ truncated and thus inactive. Yet, the mechanism of 5′ truncation is unknown. To examine whether the frequency of L1 retrotransposition is directly correlated with the length of genomic L1 insertions, we used a cell culture assay to measure retrotransposition...

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Detalhes bibliográficos
Main Authors: Farley, Alexander H., Luning Prak, Eline T., Kazazian, Haig H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373329/
https://ncbi.nlm.nih.gov/pubmed/14742665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh202
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