More active human L1 retrotransposons produce longer insertions

The vast majority of L1 insertions are 5′ truncated and thus inactive. Yet, the mechanism of 5′ truncation is unknown. To examine whether the frequency of L1 retrotransposition is directly correlated with the length of genomic L1 insertions, we used a cell culture assay to measure retrotransposition...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Nucleic Acids Res
Prif Awduron:	Farley, Alexander H., Luning Prak, Eline T., Kazazian, Haig H.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Oxford University Press 2004
Pynciau:	Articles
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373329/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh202
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!