More active human L1 retrotransposons produce longer insertions

The vast majority of L1 insertions are 5′ truncated and thus inactive. Yet, the mechanism of 5′ truncation is unknown. To examine whether the frequency of L1 retrotransposition is directly correlated with the length of genomic L1 insertions, we used a cell culture assay to measure retrotransposition...

Full description

Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Farley, Alexander H., Luning Prak, Eline T., Kazazian, Haig H.
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2004
Subjects:	Articles
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373329/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh202
Tags:	Add Tag No Tags, Be the first to tag this record!