Twin Priming: A Proposed Mechanism for the Creation of Inversions in L1 Retrotransposition

L1 retrotransposons are pervasive in the human genome. Approximately 25% of recent L1 insertions in the genome are inverted and truncated at the 5′ end of the element, but the mechanism of L1 inversion has been a complete mystery. We analyzed recent L1 inversions from the genomic database and discov...

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Bibliografische Detailangaben

Veröffentlicht in:	Genome Res
Hauptverfasser:	Ostertag, Eric M., Kazazian, Haig H.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 2001
Schlagworte:	Letter
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11731496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.205701
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