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Roles for retrotransposon insertions in human disease

Over evolutionary time, the dynamic nature of a genome is driven, in part, by the activity of transposable elements (TE) such as retrotransposons. On a shorter time scale it has been established that new TE insertions can result in single-gene disease in an individual. In humans, the non-LTR retrotr...

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書目詳細資料
發表在:Mob DNA
Main Authors: Hancks, Dustin C., Kazazian, Haig H.
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859970/
https://ncbi.nlm.nih.gov/pubmed/27158268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-016-0065-9
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