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The Minimal Active Human SVA Retrotransposon Requires Only the 5′-Hexamer and Alu-Like Domains
RNA-based duplication mediated by reverse transcriptase (RT), a process termed retrotransposition, is ongoing in humans and is a source of significant inter- and perhaps intraindividual genomic variation. The long interspersed element 1 (LINE-1 or L1) ORF2 protein is the genomic source for RT activi...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486173/ https://ncbi.nlm.nih.gov/pubmed/23007156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00860-12 |
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