Nucleotide incorporation by human DNA polymerase γ opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine

Mitochondria are major cellular targets of benzo[a]pyrene (BaP), a known carcinogen that also inhibits mitochondrial proliferation. Here, we report for the first time the effect of site-specific N(2)-deoxyguanosine (dG) and N(6)-deoxyadenosine (dA) adducts derived from BaP 7,8-diol 9,10-epoxide (BaP...

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Bibliografische gegevens

Gepubliceerd in:	Nucleic Acids Res
Hoofdauteurs:	Graziewicz, Maria A., Sayer, Jane M., Jerina, Donald M., Copeland, William C.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Oxford University Press 2004
Onderwerpen:	Articles
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14729924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh213
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