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Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase

The first occupation-associated cancers to be recognized were the sooty warts (cancers of the scrotum) suffered by chimney sweeps in 18th century England. In the 19th century, high incidences of skin cancers were noted among fuel industry workers. By the early 20th century, malignant skin tumors wer...

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Publicado en:Proc Natl Acad Sci U S A
Main Authors: Ling, Hong, Sayer, Jane M., Plosky, Brian S., Yagi, Haruhiko, Boudsocq, François, Woodgate, Roger, Jerina, Donald M., Yang, Wei
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308332100
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