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Biochemical Mechanism of Modulation of Human P-glycoprotein by Stemofoline

The resistance to chemotherapeutic drugs by cancer cells is considered to be one of the major obstacles for success in the treatment of cancer. A major mechanism underlying this multidrug resistance is the overexpression of P-glycoprotein (P-gp), resulting in an insufficient drug delivery to the tum...

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Bibliografiske detaljer
Main Authors: Chanmahasathien, Wisinee, Ohnuma, Shinobu, Ambudkar, Suresh V., Limtrakul, Pornngarm
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725602/
https://ncbi.nlm.nih.gov/pubmed/21786221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0031-1280054
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