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Ferritin light chain interacts with PEN-2 and affects γ-secretase activity
Alzheimer’s disease (AD) is primarily caused by overproduction/deposition of β-amyloid (Aβ) in the brain. Dysregulation of iron in the brain also contributes to AD. Although iron affects β-amyloid precursor protein (APP) expression and Aβ deposition, detailed role of iron in AD requires further eluc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724929/ https://ncbi.nlm.nih.gov/pubmed/23685131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.05.018 |
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