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Sorting Nexin 27 Regulates Aβ Production through Modulating γ-secretase Activity
Patients with Down syndrome (DS) invariably develop Alzheimer’s disease (AD) pathology in their 40s. We have recently found that overexpression of a chromosome 21-encoded microRNA-155 results in decreased levels of the membrane trafficking component, SNX27, diminishing glutamate receptor recycling a...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4328673/ https://ncbi.nlm.nih.gov/pubmed/25437557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.037 |
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