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Sorting Nexin 27 Regulates Aβ Production through Modulating γ-Secretase Activity
Patients with Down syndrome (DS) invariably develop Alzheimer’s disease (AD) pathology in their 40s. We have recently found that overexpression of a chromosome 21-encoded microRNA-155 results in decreased levels of the membrane trafficking component, SNX27, diminishing glutamate receptor recycling a...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014-11-01
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| Colecção: | Cell Reports |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2211124714008201 |
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