Suppression of Cytochrome P450 Reductase Enhances Long-Term Hematopoietic Stem Cell Repopulation Efficiency in Mice

BACKGROUND: Bone marrow microenvironment (niche) plays essential roles in the fate of hematopoietic stem cells (HSCs). Intracellular and extracellular redox metabolic microenvironment is one of the critical factors for the maintenance of the niche. Cytochrome P450 reductase (CPR) is an obligate elec...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhang, Yan, Dong, Fang, Zhang, Na, Cheng, Hui, Pang, Yakun, Wang, Xiaomin, Xu, Jing, Ding, Xinxin, Cheng, Tao, Gu, Jun, Yuan, Weiping
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724780/
https://ncbi.nlm.nih.gov/pubmed/23922855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069913
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