Suppression of Cytochrome P450 Reductase Enhances Long-Term Hematopoietic Stem Cell Repopulation Efficiency in Mice

BACKGROUND: Bone marrow microenvironment (niche) plays essential roles in the fate of hematopoietic stem cells (HSCs). Intracellular and extracellular redox metabolic microenvironment is one of the critical factors for the maintenance of the niche. Cytochrome P450 reductase (CPR) is an obligate elec...

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Hlavní autoři: Zhang, Yan, Dong, Fang, Zhang, Na, Cheng, Hui, Pang, Yakun, Wang, Xiaomin, Xu, Jing, Ding, Xinxin, Cheng, Tao, Gu, Jun, Yuan, Weiping
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724780/
https://ncbi.nlm.nih.gov/pubmed/23922855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069913
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