Suppression of cytochrome P450 reductase expression promotes astrocytosis in subventricular zone of adult mice

The aim of this study was to determine the role of NADPH-cytochrome P450 reductase (CPR) and CPR-dependent enzymes in neural stem cell (NSC) genesis in the brain. A mouse model with globally suppressed Cpr gene expression (Cpr-low mouse) was studied for this purpose. Cpr-low and wild-type (WT) mice...

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Hlavní autoři: Yao, Yunyi, Liu, Senyan, Wang, Yue, Yuan, Weiping, Ding, Xinxin, Cheng, Tao, Shen, Qin, Gu, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731042/
https://ncbi.nlm.nih.gov/pubmed/23727388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.05.043
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