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Neurobehavioral abnormalities in a brain-specific NADPH-cytochrome P450 reductase knockout mouse model

The aim of the present study was to test a new hypothesis that brain cytochrome P450 reductase (CPR) and CPR-dependent enzymes play important roles in behavioral performance. A mouse model with brain neuron-specific deletion of the Cpr gene (brain-Cpr-null) was recently generated. Brain-Cpr-null mic...

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Detalhes bibliográficos
Main Authors: Fang, Cheng, Bolivar, Valerie J., Gu, Jun, Yang, Weizhu, Zeitlin, Scott O., Ding, Xinxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393838/
https://ncbi.nlm.nih.gov/pubmed/22626646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.05.027
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