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Nuclear Factor of Activated T Cells c1 Mediates p21-activated Kinase 1 Activation in the Modulation of Chemokine-induced Human Aortic Smooth Muscle Cell F-actin Stress Fiber Formation, Migration, and Proliferation and Injury-induced Vascular Wall Remodeling

Recent literature suggests that cyclin-dependent kinases (CDKs) mediate cell migration. However, the mechanisms were not known. Therefore, the objective of this study is to test whether cyclin/CDKs activate Pak1, an effector of Rac1, whose involvement in the modulation of cell migration and prolifer...

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Autori principali: Kundumani-Sridharan, Venkatesh, Singh, Nikhlesh K., Kumar, Sanjay, Gadepalli, Ravisekhar, Rao, Gadiparthi N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724667/
https://ncbi.nlm.nih.gov/pubmed/23737530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.454082
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