Activation of Cytosolic Phospholipase A(2) Downstream of the Src-Phospholipase D1 (PLD1)-Protein Kinase C γ (PKCγ) Signaling Axis Is Required for Hypoxia-induced Pathological Retinal Angiogenesis

In view of understanding the mechanisms of retinal neovascularization, we had reported previously that vascular endothelial growth factor (VEGF)-induced pathological retinal angiogenesis requires the activation of Src-PLD1-PKCγ signaling. In the present work, we have identified cytosolic phospholipa...

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Hlavní autoři: Zhang, Qiuhua, Wang, Dong, Singh, Nikhlesh K., Kundumani-Sridharan, Venkatesh, Gadiparthi, Laxmisilpa, Rao, Ch. Mohan, Rao, Gadiparthi N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121394/
https://ncbi.nlm.nih.gov/pubmed/21536681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.217786
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