15-Lipoxygenase-1-enhanced Src-Janus Kinase 2-Signal Transducer and Activator of Transcription 3 Stimulation and Monocyte Chemoattractant Protein-1 Expression Require Redox-sensitive Activation of Epidermal Growth Factor Receptor in Vascular Wall Remodeling

To understand the mechanisms by which 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE) activates signal transducer and activator of transcription 3 (STAT3), we studied the role of epidermal growth factor receptor (EGFR). 15(S)-HETE stimulated tyrosine phosphorylation of EGFR in a time-dependent manne...

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Detalhes bibliográficos
Principais autores: Singh, Nikhlesh K., Wang, Dong, Kundumani-Sridharan, Venkatesh, Van Quyen, Dong, Niu, Jixiao, Rao, Gadiparthi N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121393/
https://ncbi.nlm.nih.gov/pubmed/21536676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225060
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