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Novel role of Pyk2 in vascular wall remodeling following balloon injury
OBJECTIVE: To investigate the role of Pyk2, a proline-rich non-receptor tyrosine kinase, in GPCR agonist, thrombin-induced HASMC growth and migration and injury-induced vascular wall remodeling. METHODS AND RESULTS: Thrombin, a GPCR agonist, activated Pyk2 in a time-dependent manner and inhibition o...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3885160/ https://ncbi.nlm.nih.gov/pubmed/22922962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.253112 |
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