Cyclin D1 Is a Bona Fide Target Gene of NFATc1 and Is Sufficient in the Mediation of Injury-induced Vascular Wall Remodeling

Platelet-derived growth factor BB induced cyclin D1 expression in a time- and nuclear factor of activated T cells (NFAT)-dependent manner in human aortic smooth muscle cells (HASMCs), and blockade of NFATs prevented HASMC DNA synthesis and their cell cycle progression from G(1) to S phase. Selective...

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Detalhes bibliográficos
Main Authors: Karpurapu, Manjula, Wang, Dong, Van Quyen, Dong, Kim, Tae-Kang, Kundumani-Sridharan, Venkatesh, Pulusani, Srinidhi, Rao, Gadiparthi N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823422/
https://ncbi.nlm.nih.gov/pubmed/19933579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063727
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