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The Peptidyl-prolyl Isomerase Pin1 Up-regulation and Proapoptotic Function in Dopaminergic Neurons: RELEVANCE TO THE PATHOGENESIS OF PARKINSON DISEASE
Parkinson disease (PD) is a chronic neurodegenerative disease characterized by a slow and progressive degeneration of dopaminergic neurons in substantia nigra. The pathophysiological mechanisms underlying PD remain unclear. Pin1, a major peptidyl-prolyl isomerase, has recently been associated with c...
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Main Authors: | , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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American Society for Biochemistry and Molecular Biology
2013
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724650/ https://ncbi.nlm.nih.gov/pubmed/23754278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.444224 |
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