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Molecular Cloning, Epigenetic Regulation and Functional Characterization of Prkd1 Gene Promoter in Dopaminergic Cell Culture Models of Parkinson’s Disease
We recently identified a compensatory survival role for protein kinase D1 (PKD1) in protecting dopaminergic neurons from oxidative insult. To investigate the molecular mechanism of Prkd1 gene expression, we cloned the 5’-flanking region (1620-bp) of the mouse Prkd1 gene. Deletion analyses revealed t...
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| Publicado no: | J Neurochem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839478/ https://ncbi.nlm.nih.gov/pubmed/26230914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13261 |
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