PPAR δ agonist GW0742 interacts weakly with multiple nuclear receptors including the vitamin D receptor

A high throughput screening campaign was conducted to identify small molecules with the ability to inhibit the interaction between the vitamin D receptor (VDR) and steroid receptor coactivator 2. These inhibitors represent novel molecular probes to modulate gene regulation mediated by VDR. The perox...

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Autori principali: Nandhikonda, Premchendar, Yasgar, Adam, Baranowski, Athena M., Sidhu, Preetpal S., McCallum, Megan M., Pawlak, Alan J., Teske, Kelly, Feleke, Belaynesh, Yuan, Nina Y., Kevin, Chinedum, Bikle, Daniel D., Ayers, Steven D., Webb, Paul, Rai, Ganesha, Simeonov, Anton, Jadhav, Ajit, Maloney, David, Arnold, Leggy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724348/
https://ncbi.nlm.nih.gov/pubmed/23713684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400321p
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