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Suppression of Epithelial-to-Mesenchymal Transitioning Enhances Ex Vivo Reprogramming of Human Exocrine Pancreatic Tissue Toward Functional Insulin-Producing β-Like Cells

Because of the lack of tissue available for islet transplantation, new sources of β-cells have been sought for the treatment of type 1 diabetes. The aim of this study was to determine whether the human exocrine-enriched fraction from the islet isolation procedure could be reprogrammed to provide add...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Lima, Maria João, Muir, Kenneth R., Docherty, Hilary M., Drummond, Robert, McGowan, Neil W.A., Forbes, Shareen, Heremans, Yves, Houbracken, Isabelle, Ross, James A., Forbes, Stuart J., Ravassard, Philippe, Heimberg, Harry, Casey, John, Docherty, Kevin
التنسيق: Artigo
اللغة:Inglês
منشور في: American Diabetes Association 2013
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717833/
https://ncbi.nlm.nih.gov/pubmed/23610058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1256
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