Reprogramming of human pancreatic exocrine cells to β-like cells

Rodent acinar cells exhibit a remarkable plasticity as they can transdifferentiate to duct-, hepatocyte- and islet β-like cells. We evaluated whether exocrine cells from adult human pancreas can similarly respond to proendocrine stimuli. Exocrine cells from adult human pancreas were transduced direc...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Lemper, M, Leuckx, G, Heremans, Y, German, M S, Heimberg, H, Bouwens, L, Baeyens, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572860/
https://ncbi.nlm.nih.gov/pubmed/25476775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.193
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