Suppression of Epithelial-to-Mesenchymal Transitioning Enhances Ex Vivo Reprogramming of Human Exocrine Pancreatic Tissue Toward Functional Insulin-Producing β-Like Cells

Because of the lack of tissue available for islet transplantation, new sources of β-cells have been sought for the treatment of type 1 diabetes. The aim of this study was to determine whether the human exocrine-enriched fraction from the islet isolation procedure could be reprogrammed to provide add...

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Detalhes bibliográficos
Main Authors: Lima, Maria João, Muir, Kenneth R., Docherty, Hilary M., Drummond, Robert, McGowan, Neil W.A., Forbes, Shareen, Heremans, Yves, Houbracken, Isabelle, Ross, James A., Forbes, Stuart J., Ravassard, Philippe, Heimberg, Harry, Casey, John, Docherty, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717833/
https://ncbi.nlm.nih.gov/pubmed/23610058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1256
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