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Surgical Injury to the Mouse Pancreas through Ligation of the Pancreatic Duct as a Model for Endocrine and Exocrine Reprogramming and Proliferation

Expansion of pancreatic beta cells in vivo or ex vivo, or generation of beta cells by differentiation from an embryonic or adult stem cell, can provide new expandable sources of beta cells to alleviate the donor scarcity in human islet transplantation as therapy for diabetes. Although recent advance...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: De Groef, Sofie, Leuckx, Gunter, Van Gassen, Naomi, Staels, Willem, Cai, Ying, Yuchi, Yixing, Coppens, Violette, De Leu, Nico, Heremans, Yves, Baeyens, Luc, Van de Casteele, Mark, Heimberg, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544398/
https://ncbi.nlm.nih.gov/pubmed/26273954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52765
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