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Concise Review: Macrophages: Versatile Gatekeepers During Pancreatic β-Cell Development, Injury, and Regeneration

Macrophages are classically considered detrimental for pancreatic β-cell survival and function, thereby contributing to β-cell failure in both type 1 (T1D) and 2 (T2D) diabetes mellitus. In addition, adipose tissue macrophages negatively influence peripheral insulin signaling and promote obesity-ind...

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Bibliografiske detaljer
Udgivet i:Stem Cells Transl Med
Main Authors: Van Gassen, Naomi, Staels, Willem, Van Overmeire, Eva, De Groef, Sofie, Sojoodi, Mozhdeh, Heremans, Yves, Leuckx, Gunter, Van de Casteele, Mark, Van Ginderachter, Jo A., Heimberg, Harry, De Leu, Nico
Format: Artigo
Sprog:Inglês
Udgivet: AlphaMed Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449100/
https://ncbi.nlm.nih.gov/pubmed/25848123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2014-0272
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